cancer

Agus Munoz-Garcia: From Cockroaches to Cancer Research

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Agus Munoz-Garcia, Associate Professor in the Department of Evolution, Ecology, and Organismal Biology at the Ohio State Mansfield Campus, explains his research in physiological ecology, including studies on resource allocation (how animals distribute limited nutrients among different biological functions) using a unique cockroach species that he raises in the lab. He also discusses his current research project with fellow Ohio State Professor Karl Obrietan in the Neuroscience Department, where they are investigating the possible applications of controlling regulatory proteins in the treatment of cancer.

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Dehua Pei: How Do Large Molecules Pass Through Cell Membranes?

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Dehua Pei, Distinguished Professor of Chemistry and Biochemistry, discusses his groundbreaking research on how biomolecules, particularly large proteins, traverse cell membranes. This fundamental question has significant implications for drug discovery. His team has identified a new mechanism they call vesicle budding and collapse (VBC) and is exploring its potential to deliver therapeutic agents for diseases like cancer and Alzheimer’s. Pei and host David Staley discuss the importance of combining curiosity-driven research with societal needs, aiming to solve “undruggable” diseases (those lacking drug treatments) and improve sustainable agriculture. He also describes his journey from doing fundamental research to founding four biotech companies.

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